3D Electron Microscopy Of Molecular Assemblies
Zhang Lab University of Pittsburgh School of Medicine Department of Structural Biology
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Cryo-EM (Scheduler)
Polara G2 300KV FEG, Gatan 4k x 4k CCD camera
Tecnai TF20, 200KV FEG, Gatan 4k x 4k CCD camera
Tecnai T12 120KV LaB6
FEI Vitrobot, Automated Plunger
In addition to the state-of-the-art cryo-EM instruments, our lab has access to departmental resources such as biochemical equipment and biophysical instrumentation. Among the facilities are:

X-ray Crystallography
2 FRE generators
4 detectors
Crystallization robot
Sample robot

NMR Spectroscopy
900 MHz with cryoprobe
800 MHz with cryoprobe
700 MHz with cryoprobe
600 MHz widebore
600 MHz narrow bore with cryoprobe
600 MHz narrow bore, used with specialized probes

Protein Expression and Purification
The Department also houses a 1200 sq.ft. suite to support protein expression and purification from different organisms ranging from bacteria to mammalian cells.

Computational Facilities

A gigabit ethernet backplane servers
Two room teaching lab

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